SS-31 Research Guide
What Is SS-31?
SS-31, also known as Elamipretide, MTP-131 or Bendavia, is a synthetic tetrapeptide developed to target mitochondria. It belongs to a family of compounds known as Szeto-Schiller (SS) peptides, which were specifically designed for the investigation of mitochondrial biology and cellular energy production.
Unlike many peptides that interact with cell surface receptors, SS-31 is studied for its ability to localise to the inner mitochondrial membrane, making it one of the most widely recognised mitochondria-targeting peptides within scientific research.
Understanding How SS-31 Works
SS-31 is classified as a mitochondria-targeting tetrapeptide.
Researchers have investigated how SS-31 selectively associates with cardiolipin, a phospholipid found almost exclusively within the inner mitochondrial membrane. Cardiolipin plays an important structural role in maintaining mitochondrial architecture and supporting the organisation of the electron transport chain.
By studying this interaction, researchers have explored the relationship between mitochondrial membrane integrity, cellular bioenergetics and mitochondrial function across a wide range of laboratory models.
Why Researchers Study SS-31
SS-31 has been investigated across numerous scientific disciplines, including:
- Mitochondrial biology
- Cellular bioenergetics
- Oxidative stress research
- Mitochondrial membrane biology
- Cardiolipin research
- Cellular signalling
- Healthy ageing research
Its unique mitochondrial targeting characteristics continue to make SS-31 an important subject of scientific investigation.
What Makes SS-31 Different?
Unlike growth hormone peptides, neuropeptides and melanocortin peptides, SS-31 was specifically developed to target mitochondria.
One of its defining characteristics is its interaction with cardiolipin, a phospholipid located within the inner mitochondrial membrane. Researchers have investigated this interaction extensively due to cardiolipin's importance in mitochondrial structure and function.
This unique mechanism distinguishes SS-31 from many other research peptides and has contributed to its growing prominence within mitochondrial research.
The Development of SS-31
SS-31 was developed as part of the Szeto-Schiller peptide family, a group of synthetic peptides designed to investigate mitochondrial function.
Its development represented a significant advance in mitochondrial research because it provided scientists with a compound capable of selectively localising to mitochondria without relying on conventional receptor-mediated pathways. Since then, SS-31 has become one of the most widely studied mitochondria-targeting peptides in the scientific literature.
SS-31 Compared to Other Research Compounds
SS-31
A synthetic mitochondria-targeting tetrapeptide studied for its interaction with cardiolipin and mitochondrial biology.
MOTS-C
A naturally occurring mitochondrial-derived peptide investigated within cellular metabolism and mitochondrial signalling.
NAD+
A naturally occurring coenzyme commonly studied in relation to cellular metabolism and mitochondrial function.
GHK-Cu
A naturally occurring copper-binding peptide investigated within cellular signalling and tissue biology.
Each compound possesses a distinct biological origin, structure and area of scientific investigation.
Product Specifications
Compound: SS-31
Alternative Names: Elamipretide, MTP-131, Bendavia
Quantity: 10mg
Form: Lyophilised powder
Appearance: White to off-white powder
Storage: Store refrigerated upon receipt
Testing: Independently batch tested
Research Classification: Synthetic Mitochondria-Targeting Tetrapeptide
Independent Batch Testing
At Platinum Peptides, transparency and quality assurance remain central to our approach.
Every batch undergoes independent third-party analytical testing to verify identity and purity before being released.
Why Batch Testing Matters
Identity Verification
Confirms that the material matches the labelled compound.
Purity Analysis
Provides confidence that the sample meets established quality standards.
Consistency
Helps ensure batch-to-batch reliability and reproducibility.
Transparency
Allows researchers to review independent analytical data before making purchasing decisions.
Certificates of Analysis are available for each batch where applicable.
Storage Information
Lyophilised peptides should be stored in a cool, dry environment and protected from excessive heat, moisture and direct sunlight.
Researchers should always review appropriate storage conditions relevant to their specific protocols and applications.
Frequently Asked Questions
What is SS-31?
SS-31 is a synthetic mitochondria-targeting tetrapeptide also known as Elamipretide, MTP-131 and Bendavia. It is widely studied within mitochondrial biology research.
Is SS-31 naturally occurring?
No. SS-31 is a synthetic peptide developed for scientific research.
What is Elamipretide?
Elamipretide is the scientific name commonly used for SS-31.
What is cardiolipin?
Cardiolipin is a phospholipid located primarily within the inner mitochondrial membrane and plays an important role in mitochondrial structure and function. Researchers frequently investigate the interaction between SS-31 and cardiolipin.
What type of peptide is SS-31?
SS-31 is classified as a synthetic mitochondria-targeting tetrapeptide and a member of the Szeto-Schiller peptide family.
Is SS-31 batch tested?
Yes. Platinum Peptides uses independent third-party testing to verify batch quality and purity.
How should SS-31 be stored?
Store in accordance with established peptide storage guidelines and maintain refrigeration where appropriate.
Related Research Compounds
Researchers interested in SS-31 may also wish to explore:
Important Information
This product is supplied strictly for laboratory research purposes only.
It is not intended for human consumption, therapeutic use, diagnostic use or veterinary use.
Researchers are responsible for ensuring compliance with all applicable laws, regulations and research protocols relating to the handling and use of peptide compounds.
Platinum Peptides does not provide guidance regarding dosage, administration, usage protocols or expected effects. Researchers are responsible for conducting their own independent research.